Bipartición Intestinal y Remisión de Diabetes Tipo 2

The Bipartite intestinal, Also known as bypass SASI (Single Anastomosis Sleeve Ileal), has become one of the most promising options of modern metabolic surgery for patients living with obesity and Type 2 diabetes. Unlike other techniques, it not only seeks to lose weight: it was specifically designed to transform the intestinal hormonal response that regulates glucose.

In this article, I explain what the procedure involves, what published studies in 2025 and 2026 say, and why patients in Mexico and the United States are considering this option as a real alternative for the remission of diabetes.

What is intestinal bipartition?

Intestinal bipartition is a metabolic surgery originally developed by Dr. Sergio Santoro in Brazil. The version most commonly practiced today is known as bypass SASIA gastric sleeve is performed (approximately 80% of the stomach is removed) and, in addition, the remaining stomach is connected directly to a distal portion of the small intestine (the ileum).

The result is that the food continues to be two pathsOne part passes through the natural route (duodenum and jejunum) and the other part travels directly to the ileum. This dual pathway stimulates the early release of intestinal hormones such as GLP-1 and PYY, responsible for improving insulin sensitivity and controlling appetite.

How does the intestinal bipartition help relieve type 2 diabetes?

Studies suggest that remission of diabetes after intestinal bipartition does not depend solely on weight loss. Recent research indicates that the benefit is explained by a complex interaction between the intestinal microbiota, the, the bile acids and the secretion of enterohormones in the terminal ileum.

When food reaches the distal ileum quickly, the so-called «incrine effect» is activated, which produces a powerful release of GLP-1. This hormone:

• It stimulates the production of insulin in a physiological way.
• It reduces insulin resistance in the liver and muscles.
• It reduces appetite and prolongs satiety.
• Improves the long-term health of the pancreas.

Results: What do the most recent studies say?

The research published in recent years shows very encouraging results for the Relapse of type 2 diabetes after the intestinal bipartition:

Short-term referral rates

A systematic review and meta-analysis published in 2025 reported one 88.28% remission rate of type 2 diabetes at 12 months Following the SASI procedure. Other studies conducted in the same year documented the referral of up to 92% comorbidities related to obesity, including diabetes.

Long-term results

A study published in January 2026 with follow-up over 10 years showed that the remission of diabetes was maintained in the 88% of the patients A decade after surgery, a result superior to that reported with gastric sleeve alone or traditional gastric bypass in long-evolving diabetics.

Weight loss

At 12 months, patients on average have an Loss of excess weight close to 84% And a total weight loss of 35%. These results, combined with the improved metabolic function, position the intestinal bipartition as a very competitive alternative to other bariatric surgeries.

Who is the candidate for intestinal bipartisanship?

Intestinal bipartition can be considered in patients who:

• They have poorly controlled type 2 diabetes despite medical treatment.
• They have an BMI greater than 30 with metabolic comorbidities.
• They have not had a good response with previous gastric sleeve surgery (such as revision surgery).
• They are looking for a metabolic procedure with a low risk of serious nutritional deficiencies, compared to the classic bypass procedure.

Each case must be evaluated individually. Factors such as the duration of diabetes, the level of peptide C, and pancreatic reserve directly influence the likelihood of remission.

Advantages compared to other bariatric surgeries

• Greater metabolic effect that the gastric sleeve alone, thanks to intestinal hormonal stimulation.
• Lower risk of nutritional deficiencies that the classic Roux Y gastric bypass, since the natural passage through the duodenum is preserved.
• Accessible endoscopyThe stomach and duodenum can still be evaluated by endoscopy.
• Partial reversibilityThe anastomosis can be adjusted or closed if complications arise.

Risks and Considerations

Like any major surgery, intestinal bisection is not without risks. The medical literature has reported isolated cases of malnutrition or chronic diarrhea when the length of the intestinal tract is not properly configured. Therefore, it is essential to seek the advice of a bariatric surgeon with specific experience in this technique, as the results depend largely on surgical precision.

Medical advice: The information in this article is for educational purposes and does not replace medical consultation. Results vary depending on each patient.

Cost of intestinal bipartition in Mexico

One of the reasons why patients from Texas and other parts of the United States choose Piedras Negras, Coahuila (just 15 minutes from Eagle Pass, TX), is the access to high-level metabolic surgery at a fraction of the cost in the United States, with certified surgeons and accredited hospitals.

Frequently Asked Questions

Does the intestinal bifidobacteria cure type 2 diabetes?

It is not spoken of as «cure», but as remission. Studies suggest that more than 80% of patients maintain normal glucose levels without medication for several years, although lifelong follow-up is required.

How long does the recovery take?

Most patients return to normal activities between 2 and 3 weeks. Intense physical activity is recommended starting at 4 to 6 weeks.

Can I have intestinal bipartition if I already have a gastric sleeve?

Yes. In fact, bipartisanship is an excellent Revision surgery For patients who regained weight or whose diabetes returned after a previous sleeve, as it adds the metabolic component without the need to remove more stomach.

Will I have to take supplements for life?

A multivitamin complex and periodic laboratory tests are recommended, although the risk of serious deficiencies is lower than with classic gastric bypass.

Is the intestinal bipartition reversible?

The gastric sleeve is not reversible, but the intestinal anastomosis can be modified or closed if the patient develops nutritional complications that do not respond to medical treatment.

Conclusion: an option with growing scientific support

Intestinal bipartition represents an important advance in metabolic surgery. Studies in 2025 and 2026 confirm rates of remission of type 2 diabetes of over 85% in the short and long term, with good nutritional safety when the technique is performed by an experienced surgeon.

If you live with obesity and type 2 diabetes and want to know if you are a candidate for intestinal bipartition, schedule a free evaluation with Dr. Cristóbal Garza, a bariatric surgeon in Piedras Negras, Coahuila.